On the mechanism of glucose protection against alloxan toxicity
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چکیده
منابع مشابه
The Mechanism of Alloxan Protection in Experimental Atherosclerosis
Experiments were performed to compare the effects of cholesterol feeding in (a) control rabbits, (b) alloxan-diabetic rabbits, and (c) rabbits injected with alloxan while the pancreas was temporarily occluded from the circulation. The alloxan-diabetic rabbits consumed significantly higher quantities of cholesterol and food and had serum cholesterol and lipoprotein (S(f) 5-9 and S(f) 16-30) conc...
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متن کاملStudies on the mechanism of alloxan hypoglycemia.
It is well known that when alloxan is injected intravenously into rabbits, dogs, and monkeys an initial hyperglycemia is followed by a transient hypoglycemia, leading to death of the animals from hypoglycemic convulsions. If the hypoglycemia is prevented by repeated intravenous injections of glucose, the animals survive and permanent hyperglycemia and diabetes develop. The cause of the transien...
متن کاملOn the Mechanism of Alloxan Hypoglycemia
Intravenous injection of alloxan into rabbits, rats, dogs, monkeys, etc., produces a brief hyperglycemia, then a transient hypoglycemia, which in the case of rabbits is severe enough to cause convulsions and death, unless counteracted by repeated injections of glucose, and finally a permanent diabetic hyperglycemia. The cause of the transient hypoglycemia has had various explanations. Goldner a...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1971
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf01211877